GLP-1 Clinics in Sioux Falls

Sioux Falls, South Dakota

10 website-confirmed clinics
2 accept insurance
from $199/mo

GLP-1 Weight Loss Clinics in Sioux Falls, South Dakota

GLPFinders lists 10 website-confirmed GLP-1 clinics in Sioux Falls, South Dakota. Providers offer both semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound). 2 clinics accept insurance.

✓ Insurance accepted

GLP-1 prices and clinic data in Sioux Falls, SD

Clinics listed
10
website-confirmed
Disclosed price
$199
median $199/mo · 1 of 10 publish one
Semaglutide
3
clinics list it as a service
Tirzepatide
3
clinics list it as a service
Accept insurance
2
per their own website

One Sioux Falls clinic publishes a monthly price: $199.

4 of 10 listings name the medications they offer: 3 list semaglutide (Ozempic, Wegovy) and 3 list tirzepatide (Mounjaro, Zepbound). The rest do not say publicly, so ask when you call.

Monthly prices published by Sioux Falls clinics on their own websites, lowest first.
ClinicDisclosed price
Gameday Men's Health$199/mo

Counts cover the 10 website-confirmed Sioux Falls listings in this directory as of September 2026. Blank fields mean the clinic does not publish that detail, not that it is unavailable.

Dosing, trial results, side effects, and what each one costs through insurance, a manufacturer program, or cash-pay.

SemaglutideTirzepatideWegovyZepboundWhat clinics charge nationally

The Confidence Collective

5128 S. Cliff Ave, Sioux Falls, SD

SemaglutideTirzepatide
$750

Accelerate Wellness

Sioux Falls, SD

Avera Comprehensive Weight Management

0

Sioux Falls, SD

Insurance

Gameday Men's Health

0

4908 E Rosa Parks Pl, Sioux Falls, SD

Insurance
From $199/mo

BeyondMD

0

Sioux Falls, SD

Semaglutide

Aspire Health

0

Sioux Falls, SD

WegovyZepbound

Vital Flow Infusions

0

119 S Main Ave, Sioux Falls, SD

iv&co

0

345 N. Reid Pl., Suite 123, Sioux Falls, SD

SummaUp

0

Sioux Falls, SD

Tirzepatide
$199

CNOS

0

Sioux Falls, SD

GLP-1 Clinics in Sioux Falls — FAQ

Where can I get GLP-1 injections in Sioux Falls, South Dakota?

GLPFinders lists 10 website-confirmed GLP-1 providers in Sioux Falls, South Dakota. Public clinic websites mention semaglutide or tirzepatide services. Compare available details and confirm directly.

How much does semaglutide cost in Sioux Falls?

One Sioux Falls clinic publishes a monthly price: $199. Most clinics publish nothing, so the figure you are quoted depends on the dose, whether the medication is branded or compounded, and what the visit and lab work cost on top. 2 Sioux Falls clinics on GLPFinders state that they accept insurance, which can reduce what you pay.

Do GLP-1 clinics in Sioux Falls accept insurance?

Yes — 2 GLP-1 clinics in Sioux Falls listed on GLPFinders accept insurance. Coverage depends on your specific plan, medical history, and which medication is prescribed. Contact the clinic directly to verify your benefits before booking.

What is the difference between semaglutide and tirzepatide?

Semaglutide (Ozempic, Wegovy) is a GLP-1 receptor agonist that reduces appetite and slows digestion. Tirzepatide (Mounjaro, Zepbound) is a dual GIP/GLP-1 receptor agonist that typically produces greater weight loss — up to 22% of body weight in clinical trials versus approximately 15% for semaglutide. A GLP-1 provider in Sioux Falls can evaluate your health history and help determine which medication is the right fit for you.

What should I expect at my first GLP-1 consultation in Sioux Falls?

At your first GLP-1 consultation, a provider will review your medical history, current weight, BMI, and any existing conditions such as type 2 diabetes, high blood pressure, or sleep apnea. They may order basic labs (blood glucose, A1C, thyroid panel) before prescribing. If approved, you'll receive a starting dose of semaglutide or tirzepatide — typically low to minimize side effects — with a plan to titrate up over several weeks. Most Sioux Falls clinics offer follow-up appointments every 4–8 weeks to monitor progress and adjust dosing.